Jingyu ZHANG¶

zhang.jing.yu@outlook.com

Master of Science in Medicinal Chemistry

Peking Union Medical College (Tsinghua University Health Science Centre)

About me¶

I am Jingyu Zhang, a master's graduate specializing in medicinal chemistry. I completed my studies at Peking Union Medical College (Tsinghua University Health Science Centre) from September 2021 to June 2024.

I completed my bachelor's degree in pharmacy at Shandong University, where I engaged in a range of theoretical courses related to pharmaceutical research. These courses encompassed Molecular Biology, Organic Chemistry, Biochemistry, and more, along with hands-on laboratory work. Through these experiences, I gradually cultivated a strong interest in pharmaceutical research and honed my critical thinking skills.

I possess a deep-seated dedication and a strong sense of responsibility in all that I undertake. Once I set my mind on a goal, I invest my full attention and effort until it is successfully achieved. This steadfast approach has been shaped by my roles as a chemistry tutor, a study committee member, a sister, and a daughter. As for my leisure pursuits, I indulge in running during my free time to maintain a healthy body and to alleviate occasional negative emotions. Additionally, I find solace in reading books, a practice that allows me to unwind my mind and engage in self-reflection.

Research Interests¶

Biosynthesis/Synthetic Biology

Natural Product Chemistry

Education¶

Master of Science in Medicinal Chemistry, 2024 (expected)

Peking Union Medical College (Tsinghua University Health Science Center), Beijing, China

Supervisor: Prof. Shuanggang Ma
Major Courses: Natural Product Chemistry (83 / 100), Natural Product Structure Modification (82 / 100), Spectral Analysis (90 / 100), Advanced Natural Medicinal Chemistry (87 / 100)

Bachelor of Science in Pharmacy, 2021

Marine College, Shandong University (SDU), Shandong, China

Major Courses: Organic Chemistry (98 / 100), Biochemistry (94 / 100), Molecular Biology (95.2 / 100), Genetic Engineering (91 / 100), Medicinal Chemistry (87 / 100)

Research Experience¶

Chemical Composition and Biological Activity Research of the Roots and Stem Bark of Illicium brevistylum A.C.Smith (Sept. 2021 – June 2024, details)
Isolation, Identification, and Activity Study of Secondary Metabolites from Zostera marina L. L (Jul. 2021, details)
Development of a Ginger Weight Loss Biscuit (Oct. 2018 – Sept. 2019, details)
Hormonal Regulation of Saltwater Irrigation Efficiency in Maize Seedlings (Jul. 2018 – May 2019, details)
Screening of Inorganic Fungicides Against the Skin Ulceration Disease of Stichopus japonicus (Jul. 2018 – May 2019, details)

Publications¶

Zhang J Y. Explore the dawn of cancer treatment. Business Story. 2018(10):2.DOI:CNKI:SUN:SGUS.0.2018-10-116. (in Chinese)
Yang J, Zhang J P, Gao R M, Li W R, Zhang J Y, et al. Cadinane sesquiterpenes from the stems and branches of Illicium ternstroemioides. J. Asian Nat. Prod. Res. 2024, 26(2), 204-213.
Yang J, Li W R, Wang Q R, Zhang J Y, et al. Prenylated C₆-C₃ derivatives from the root of Illicium ternstroemioides with antiviral activity. J. Asian Nat. Prod. Res. 2024, 26(4), 452-464.
Zhang J Y, Yang H L, Li W R, et al. Bioactive prenylated C₆-C₃ derivatives from the roots of Illicium brevistylum. J. Asian Nat. Prod. Res. doi: 10.1080/10286020.2024.2365437. (Online ahead of print)

Junior High School Chemistry Tutor, Weihai, China (May 2021 - Jul. 2021, details)
Summer Social Practice, SDU: OHT Oral History Research Team (Jul. 2018, details)
Summer Social Practice, SDU: Azure Voice Research Team (Jul. 2019, details)

Honors¶

Best Graduation Thesis Award (Top 1), SDU, Jun. 2021
Distinguished Reader Award, SDU, Jun. 2021
First Place Scholarship, SDU, Sept. 2019
National Computer Rank Examination Certificate of level 3, Sept. 2019
Distinguished Research Assistant Award, SDU, Jul. 2019
Undergraduate Research Training Program Project - Third Place, SDU, May 2019
Sixth place, Women's 4x100m Relay Finals, SDU, May 2019
Third Prize, 4th "Disang Cup" College Students' Chinese Classics Recitation Competition, May 2019
National Computer Rank Examination Certificate of level 2, Mar. 2019
Third Prize, 9th "Liugong Island Cup" College Students' Ideological and Political Style Contest (team captain), Nov. 2018
Second Place Scholarship, SDU, Sept. 2018
Second Prize, "Shandong University Group Gymnastics" Competition, May 2018
First Place Scholarship, PUMC, Nov. 2023
Outstanding Postgraduate Student Award, PUMC, Nov. 2023

Skills¶

Bacterial Culture: Proficient in solid and liquid culture techniques, as well as microbial fermentation.
Structural Analysis: Skilled in using UV, IR, MS, NMR and X-ray diffraction.
ChemDraw and MestReNova: Proficient in drawing chemical structures and processing NMR data.
Natural Product Isolation: Experienced in chromatographic methods (including silica gel column chromatography and high-performance liquid chromatography).
Protein Isolation and Purification: Skilled in protein purification, ultrafiltration and SDS-PAGE.

Hobbies¶

Jogging: Engaging in regular jogging not only improves myocardial function and resilience but also enhances my endurance while fostering the spirit of perseverance and resilience.
Delving into Classical Poetry: I have consistently upheld the practice of making notes and appreciating classical poetry. Immersing myself in the world of ancient poetry enables me to attain tranquility, a state conducive to productive scientific research. Whenever I find myself in a state of restlessness, I turn to poetry. The profound meanings and melodic cadence of poetry embody the essence of Chinese culture.